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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human SIRPG/SIRP gamma/CD172g.
SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal-regulatory protein beta 2; Signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRP-b2; SIRP-beta-2; SIRP-gamma
基因别名: bA77C3.1; CD172g; SIRP-B2; SIRPB2; SIRPG; SIRPgamma
UniProt ID: (Human) Q9P1W8
Entrez Gene ID: (Human) 55423