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SLC10A2 Antibody (PA5-18990) in IHC (P)
Immunohistochemistry analysis of SLC10A2 Polyclonal Antibody (Product # PA5-18990) was performed on a pig ileum fixed in 10% formalin for 24 hours. To expose target proteins, antigen retrieval was performed by heating tissues in a pressure cooker for 10 minutes in 10mM sodium citrate buffer (pH 6.0). Following antigen retrieval, endogenous peroxidases were blocked with 3% hydrogen peroxide for 10 min at roo... View More
产品信息
PA5-18990
产品规格
种属反应
Mouse
已发表种属
Dog
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (DETNKGFQPDEK) corresponding to the C-terminus amino acids of Slc10a2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10981375
产品详细信息
This antibody is predicted to react with rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); mutations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Apical sodium-dependent bile acid transporter; ASBT; IBAT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2
基因别名: ASBT; ISBT; Ntcp2; Slc10a2
UniProt ID: (Mouse) Q925U7
Entrez Gene ID: (Mouse) 20494
