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产品信息
H00004891-M06
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2F7
抗原
SLC11A2 (NP_000608, 1 a.a. approximately 65 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MVLGPEQKMS DDSVSGDHGE SASLGNINPA YSNPSLSQSP GDSEEYFATY FNEKISIPEE EYSCF
靶标信息
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dct-1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Natural resistance-associated macrophage protein 2; NRAMP 2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2
基因别名: AHMIO1; DCT1; DMT1; NRAMP2; OK/SW-cl.20; SLC11A2
UniProt ID: (Human) P49281
Entrez Gene ID: (Human) 4891
copper ion transmembrane transporter activity
iron ion transmembrane transporter activity
manganese ion transmembrane transporter activity
protein binding
hydrogen ion transmembrane transporter activity
cadmium ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
ferrous iron transmembrane transporter activity
lead ion transmembrane transporter activity
solute:proton symporter activity
ferrous iron uptake transmembrane transporter activity
transferrin transmembrane transporter activity
cadmium ion binding
transition metal ion transmembrane transporter activity
secondary carrier transporter
heme biosynthetic process
cobalt ion transport
copper ion transport
manganese ion transport
cellular iron ion homeostasis
learning or memory
response to iron ion
ferrous iron transport
lead ion transport
transferrin transport
copper ion transmembrane transport
dendrite morphogenesis
erythrocyte development
multicellular organismal iron ion homeostasis
cadmium ion transmembrane transport
ferrous iron import
manganese ion transmembrane transport
hydrogen ion transmembrane transport
ferrous iron transmembrane transport
