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OriGene

SLC18A2 Monoclonal Antibody (OTI9E11), TrueMAB™

查看其他16个VMAT2抗体

说明书

实验方案

技术支持

货号 CF500506

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100 µg

说明书

实验方案

技术支持

抗体检测数据 (6)

Application

SLC18A2 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 6

SLC18A2 Antibody (CF500506) in ICC/IF

Anti-SLC18A2 mouse monoclonal antibody (TA500506) Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SLC18A2(RC221342).

SLC18A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SLC18A2 Antibody in Flow Cytometry (Flow)

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产品信息

CF500506

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000

免疫组化（石蜡） (IHC (P))

1:50

免疫细胞化学 (ICC/IF)

1:100

流式细胞分析 (Flow)

1:100

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

OTI9E11

抗原

Full-length protein expressed in 293T cell transfected with human SLC18A2 expression vector.

查看免疫原

偶联物

Unconjugated

形式

Lyophilized

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 8% trehalose

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

靶标信息

VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2

基因别名: SLC18A2; SVAT; SVMT; VAT2; VMAT2

UniProt ID: (Human) Q9H3P6

Entrez Gene ID: (Human) 6571

功能

amine transmembrane transporter activity drug binding monoamine transmembrane transporter activity serotonin transmembrane transporter activity enzyme binding heat shock protein binding secondary carrier transporter

参与通路

response to amphetamine serotonin transport chemical synaptic transmission neurotransmitter secretion aging locomotory behavior response to herbicide post-embryonic development response to zinc ion aminergic neurotransmitter loading into synaptic vesicle monoamine transport dopamine transport insulin secretion endocytic recycling cellular response to drug sequestering of neurotransmitter response to cocaine glucose homeostasis response to starvation response to corticosterone negative regulation of neurotransmitter transport transmembrane transport cellular response to ammonium ion neurotransmitter loading into synaptic vesicle negative regulation of reactive oxygen species biosynthetic process