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Proteintech

SLC19A3 Polyclonal Antibody

11 篇参考文献

查看其他6个SLC19A3抗体

说明书

实验方案

技术支持

货号 13407-1-AP

此产品在中国无法购买

150 µL

说明书

实验方案

技术支持

抗体检测数据 (7)

Application

图: 1 / 7

SLC19A3 Antibody (13407-1-AP) in WB

Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 13407-1-AP (SLC19A3 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours.

SLC19A3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

产品信息

13407-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看10篇已发表文章 10篇已发表文章

免疫细胞化学 (ICC/IF)

Assay-dependent

查看1篇已发表文章 1篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

SLC19A3 Fusion Protein Ag4053 (188-315 aa encoded by BC032014)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.6 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: LFLPMPKKS MFFHAKPSRE IKKSSSVNPV LEETHEGEAP GCEEQKPTSE ILSTSGKLNK GQLNSLKPSN VTVDVFVQWF QDLKECYSSK RLFYWSLWWA FATAGFNQVL NYVQILWDYK APSQDSSIY (188-315 aa encoded by BC032014)

靶标信息

SLC19A3 encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia.

Nature communications

Sheikh A,Tumala B,Vickers TJ,Martin JC,Rosa BA,Sabui S,Basu S,Simoes RD,Mitreva M,Storer C,Tyksen E,Head RD,Beatty W,Said HM,Fleckenstein JM

Sat Nov 12 00:00:00 UTC 2022

Impact of Metformin Treatment on Human Placental Energy Production and Oxidative Stress.

Frontiers in cell and developmental biology

Tarry-Adkins JL,Robinson IG,Reynolds RM,Aye ILMH,Charnock-Jones DS,Jenkins B,Koulmann A,Ozanne SE,Aiken CE

Wed Feb 01 00:00:00 UTC 2023

Human adipose tissue gene expression of solute carrier family 19 member 3 (SLC19A3); relation to obesity and weight-loss.

Obesity science & practice

Pereira MJ,Andersson-Assarsson JC,Jacobson P,Kamble P,Taube M,Sjöholm K,Carlsson LMS,Svensson PA

Tue Feb 01 00:00:00 UTC 2022

Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters.

The Journal of biological chemistry

Sabui S,Ramamoorthy K,Romero JM,Simoes RD,Fleckenstein JM,Said HM

Tue Feb 01 00:00:00 UTC 2022

Chronic Voluntary Alcohol Drinking Causes Anxiety-like Behavior, Thiamine Deficiency, and Brain Damage of Female Crossed High Alcohol Preferring Mice.

Frontiers in pharmacology

Xu H,Li H,Liu D,Wen W,Xu M,Frank JA,Chen J,Zhu H,Grahame NJ,Luo J

Sat Sep 25 00:00:00 UTC 2021

Proinflammatory cytokines inhibit thiamin uptake by human and mouse pancreatic acinar cells: involvement of transcriptional mechanism(s).

American journal of physiology. Gastrointestinal and liver physiology

Anandam KY,Srinivasan P,Yasujima T,Al-Juburi S,Said HM

Fri Jan 01 00:00:00 UTC 2021

CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.

Science translational medicine

Picó S,Parras A,Santos-Galindo M,Pose-Utrilla J,Castro M,Fraga E,Hernández IH,Elorza A,Anta H,Wang N,Martí-Sánchez L,Belloc E,Garcia-Esparcia P,Garrido JJ,Ferrer I,Macías-García D,Mir P,Artuch R,Pérez B,Hernández F,Navarro P,López-Sendón JL,Iglesias T,Yang XW,Méndez R,Lucas JJ

Wed Sep 29 00:00:00 UTC 2021

Effects of Chronic Voluntary Alcohol Drinking on Thiamine Concentrations, Endoplasmic Reticulum Stress, and Oxidative Stress in the Brain of Crossed High Alcohol Preferring Mice.

Neurotoxicity research

Xu H,Liu D,Chen J,Li H,Xu M,Wen W,Frank JA,Grahame NJ,Zhu H,Luo J

Fri Nov 01 00:00:00 UTC 2019

Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy.

PloS one

Flønes I,Sztromwasser P,Haugarvoll K,Dölle C,Lykouri M,Schwarzlmüller T,Jonassen I,Miletic H,Johansson S,Knappskog PM,Bindoff LA,Tzoulis C

Mon Jul 25 00:00:00 UTC 2016

Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy.

PloS one

Flønes I,Sztromwasser P,Haugarvoll K,Dölle C,Lykouri M,Schwarzlmüller T,Jonassen I,Miletic H,Johansson S,Knappskog PM,Bindoff LA,Tzoulis C

Mon Jul 25 00:00:00 UTC 2016

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

生物信息学

蛋白别名: solute carrier family 19 (sodium/hydrogen exchanger), member 3; solute carrier family 19 (thiamine transporter), member 3; Solute carrier family 19 member 3; solute carrier family 19, member 3; Thiamine transporter 2; ThTr-2

基因别名: A230084E24Rik; AI788884; BBGD; SLC19A3; THMD2; THTR2

UniProt ID: (Human) Q9BZV2, (Mouse) Q99PL8

Entrez Gene ID: (Human) 80704, (Rat) 316559, (Mouse) 80721

功能

thiamine transmembrane transporter activity thiamine uptake transmembrane transporter activity folic acid transporter activity transporter

参与通路

thiamine-containing compound metabolic process thiamine transmembrane transport drug transmembrane transport transport folic acid transport thiamine transport