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产品信息
PA5-75775
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human SLC22A1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719503
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; hOCT1; mOCT1; Organic cation transporter 1; rOCT1; solute carrier family 22 (organic cation transporter), member 1; Solute carrier family 22 member 1; solute carrier family 22, member 1; SYK
基因别名: HOCT1; Lx1; OCT1; oct1_cds; Orct; Orct1; Roct1; SLC22A1
UniProt ID: (Human) O15245, (Rat) O35882, (Mouse) O08966
Entrez Gene ID: (Human) 6580, (Rat) 24904, (Mouse) 20517
acetylcholine transmembrane transporter activity
dopamine transmembrane transporter activity
norepinephrine transmembrane transporter activity
protein binding
secondary active organic cation transmembrane transporter activity
organic cation transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
protein homodimerization activity
monoamine transmembrane transporter activity
identical protein binding
transporter activity
ion transmembrane transporter activity
transmembrane transporter activity
secondary carrier transporter
neurotransmitter transport
drug transmembrane transport
establishment or maintenance of transmembrane electrochemical gradient
organic cation transport
quaternary ammonium group transport
dopamine transport
norepinephrine transport
epinephrine transport
protein homooligomerization
ammonium transmembrane transport
acetate ester transport
cation transport
monoamine transport
cation transmembrane transport
transport
ion transport
ion transmembrane transport
transmembrane transport
