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SLC22A3 Antibody (MA5-37983) in IHC (P)
Immunohistochemistry analysis of SLC22A3 in paraffin-embedded human liver cancer. Samples were incubated with SLC22A3 Monoclonal antibody (Product # MA5-37983) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
MA5-37983
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC2285
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 301-450 of human SLC22A3/OCT3 (O75751)
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897901
产品详细信息
Positive Samples: PC-3, Mouse liver
Immunogen sequence: GDKALQILRR IAKCNGKYLS SNYSEITVTD EEVSNPSFLD LVRTPQMRKC TLILMFAWFT SAVVYQGLVM RLGIIGGNLY IDFFISGVVE LPGALLILLT IERLGRRLPF AASNIVAGVA CLVTAFLPEG IAWLRTTVAT LGRLGITMAF
靶标信息
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-Oct; EMT; EMT organic cation transporter 3; Extraneuronal monoamine transporter; OCT3; Organic cation transporter 3; solute carrier family 22 (extraneuronal monoamine transporter), member 3; solute carrier family 22 (organic cation transporter), member 3; Solute carrier family 22 member 3; solute carrier family 22, member 3
基因别名: EMT; EMTH; OCT3; Orct3; SLC22A3; Slca22a3
UniProt ID: (Human) O75751, (Mouse) Q9WTW5
Entrez Gene ID: (Human) 6581, (Mouse) 20519
dopamine transmembrane transporter activity
protein binding
organic cation transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
toxin transporter activity
transporter activity
ion transmembrane transporter activity
transmembrane transporter activity
secondary carrier transporter
drug transmembrane transport
organic cation transport
quaternary ammonium group transport
dopamine transport
regulation of appetite
histamine uptake
ammonium transmembrane transport
mitophagy in response to mitochondrial depolarization
toxin transport
transport
ion transport
monoamine transport
ion transmembrane transport
histamine transport
transmembrane transport
cation transmembrane transport
