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Quantity: 100 µg IgG per vial
SLC26A3 is a chloride/bicarbonate exchanger that is involved in absorption inside the colon. SLC26A3 helps mediate electrolyte and fluid absorption. The protein encoded by the SLC26A3 gene is a transmembrane glycoprotein that functions as a sulfate transporter, and it is localized to the mucosa. The chloride ions transported by SLC26A3 cross the cell membrane in exchange for biocarbonate ions. SLC26A3 is localized in the mucosa of the lower intestinal tract, specifically the apical membrane of the columnar epithelium and in some goblet cells. Diseases associated with SLC26A3 protein dysfunction include congenital chloride diarrhea and congenital secretory chloride diarrhea 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chloride anion exchanger; Down-regulated in adenoma; down-regulated in adenoma protein; Protein DRA; solute carrier family 26 (anion exchanger), member 3; Solute carrier family 26 member 3; solute carrier family 26, member 3
基因别名: 9030623B18Rik; 9130013M11Rik; AV376035; CLD; DRA; SLC26A3
UniProt ID: (Human) P40879, (Mouse) Q9WVC8, (Rat) Q924C9
Entrez Gene ID: (Human) 1811, (Mouse) 13487, (Rat) 114629
分子生物学功能:
transporter