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产品信息
PA5-50574
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues near the C terminal of human solute carrier family 27 (fatty acid transporter), member 1
偶联物
形式
Liquid
浓度
1.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636027
产品详细信息
The antibody detects endogenous levels of total FATP1 / SLC27A1 protein.
靶标信息
SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ACSVL5FATP-1; Arachidonate--CoA ligase; EC 6.2.1; FATP-1; Fatty acid transport protein 1; FLJ00336; Long-chain fatty acid transport protein 1; Long-chain-fatty-acid--CoA ligase; MGC71751; solute carrier family 27 (fatty acid transporter), member 1; Solute carrier family 27 member 1; Very long-chain acyl-CoA synthetase
基因别名: ACSVL5; FATP; FATP-1; FATP1; SLC27A1
UniProt ID: (Human) Q6PCB7
Entrez Gene ID: (Human) 376497
medium-chain fatty acid transport
long-chain fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
phosphatidic acid biosynthetic process
phosphatidylglycerol biosynthetic process
phosphatidylcholine biosynthetic process
phosphatidylserine biosynthetic process
phosphatidylinositol biosynthetic process
response to cold
long-chain fatty acid transport
positive regulation of heat generation
cardiolipin biosynthetic process
response to insulin
adiponectin-activated signaling pathway
negative regulation of phospholipid biosynthetic process
positive regulation of protein serine/threonine kinase activity
