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产品信息
PA5-65424
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2664675
产品详细信息
Immunogen sequence: YARYYMRPVLA AHVFSGEEEL PQDSLSAPSV ASRFIDSHTP PLRPILKKT
Highest antigen sequence identity to the following orthologs - mouse 64%, rat 62%.
靶标信息
SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis. SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter. Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus.
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生物信息学
蛋白别名: Equilibrative nucleoside transporter 3; hENT3; solute carrier family 29 (equilibrative nucleoside transporter), member 3; solute carrier family 29 (nucleoside transporters), member 3; Solute carrier family 29 member 3
基因别名: ENT3; HCLAP; HJCD; PHID; SLC29A3; UNQ717/PRO1380
UniProt ID: (Human) Q9BZD2
Entrez Gene ID: (Human) 55315
