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Immunogen sequence: ITFKPIAPSG QNATCTRYSY CNECMLDPDC GFCYKMNKST VIDSSCVPVN KASTNEAAWG RCENETKFKT EDI
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 88%.
SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: H(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; proton (H+) myo-inositol symporter; Proton myo-inositol cotransporter; solute carrier family 2 (facilitated glucose transporter), member 13; Solute carrier family 2 member 13
基因别名: HMIT; SLC2A13
UniProt ID: (Human) Q96QE2
Entrez Gene ID: (Human) 114134