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SLC2A13 Antibody (PA5-97325) in WB
Western blot analysis of SLC2A13 in extracts of various cell lines. Samples were incubated with SLC2A13 Polyclonal antibody (Product # PA5-97325) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-97325
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 564-648 of human SLC2A13 (NP_4431173)
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2809127
产品详细信息
Immunogen sequence: LHTAEYLTYY GAFFLYAGFA AVGLLFIYGC LPETKGKKLE EIESLFDNRL CTCGTSDSDE GRYIEYIRVK GSNYHLSDND ASDVE; Positive Samples: HeLa, SH-SY5Y, HepG2, NCI-H460, HT-1080, K-562, Mouse kidney, Mouse pancreas, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; hmit; proton (H+) myo-inositol symporter; Proton myo-inositol cotransporter; proton myo-inositol symporter; solute carrier family 2 (facilitated glucose transporter), member 13; Solute carrier family 2 member 13
基因别名: 6530403A04; A630029G22Rik; AI505012; Gm308; HMIT; SLC2A13
UniProt ID: (Human) Q96QE2, (Rat) Q921A2, (Mouse) Q3UHK1
Entrez Gene ID: (Human) 114134, (Rat) 171147, (Mouse) 239606
