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SLC39A8 (extracellular) Antibody (PA5-111913) in IHC (F)
Immunohistochemistry analysis of SLC39A8 in perfusion-fixed, frozen rat hippocampus tissue sections using SLC39A8 (extracellular) Antibody (Product # PA5-111913) at a dilution of 1:200, followed by goat-anti-rabbit-AlexaFluor-488. ZIP8 staining (green) appears in interneurons (arrows) adjacent to the granular layer (GL). Cell nuclei are stained with DAPI (blue).
产品信息
PA5-111913
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 221-234 of rat ZIP8 (2nd extracellular loop)
偶联物
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2857321
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)KTYGQND HTHFRND
Homology: Mouse amino acid residues identical; human - 12/14 amino acid residues identical.
靶标信息
The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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