Product References
Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptake.
Cell death discovery
Liu Y,Liu C,Pan Y,Zhou J,Ju H,Zhang Y
Published figure using SLC5A5 monoclonal antibody (Product # MA5-12308) in Immunocytochemistry
Thu Oct 20 00:00:00 UTC 2022
Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptake.
Cell death discovery
Liu Y,Liu C,Pan Y,Zhou J,Ju H,Zhang Y
Published figure using SLC5A5 monoclonal antibody (Product # MA5-12308) in Immunocytochemistry
Thu Oct 20 00:00:00 UTC 2022
Regulation of the Tpo, Tg, Duox2, Pds, and Mct8 genes involved in the synthesis of thyroid hormones after subchronic exposure to sodium nitrate in female Wistar rats.
Environmental toxicology
Ríos-Sánchez E,González-Zamora A,Gonsebatt Bonaparte ME,Meza Mata E,González-Delgado MF,Zámago Amaro A,Pérez-Morales R
MA5-12308 was used in Immunohistochemistry (Paraffin), Western Blot to explore the effect of subchroic exposure to sodium nitrate at varying concentrations on Tpo, Tg, Duox2, Pds and Mct8 geses regulating the thryroid hormone profile. Hematological and histochemical changes within thyroid and liver were also investigated.
Wed Dec 01 00:00:00 UTC 2021
Regulation of the Tpo, Tg, Duox2, Pds, and Mct8 genes involved in the synthesis of thyroid hormones after subchronic exposure to sodium nitrate in female Wistar rats.
Environmental toxicology
Ríos-Sánchez E,González-Zamora A,Gonsebatt Bonaparte ME,Meza Mata E,González-Delgado MF,Zámago Amaro A,Pérez-Morales R
MA5-12308 was used in Immunohistochemistry (Paraffin), Western Blot to explore the effect of subchroic exposure to sodium nitrate at varying concentrations on Tpo, Tg, Duox2, Pds and Mct8 geses regulating the thryroid hormone profile. Hematological and histochemical changes within thyroid and liver were also investigated.
Wed Dec 01 00:00:00 UTC 2021
FOXA1 Regulation Turns Benzamide HDACi Treatment Effect-Specific in BC, Promoting NIS Gene-Mediated Targeted Radioiodine Therapy.
Molecular therapy oncolytics
Rathod M,Kelkar M,Valvi S,Salve G,De A
Published figure using SLC5A5 monoclonal antibody (Product # MA5-12308) in Western Blot
Wed Dec 16 00:00:00 UTC 2020
FOXA1 Regulation Turns Benzamide HDACi Treatment Effect-Specific in BC, Promoting NIS Gene-Mediated Targeted Radioiodine Therapy.
Molecular therapy oncolytics
Rathod M,Kelkar M,Valvi S,Salve G,De A
Published figure using SLC5A5 monoclonal antibody (Product # MA5-12308) in Western Blot
Wed Dec 16 00:00:00 UTC 2020
Rodents Versus Pig Model for Assessing the Performance of Serotype Chimeric Ad5/3 Oncolytic Adenoviruses.
Cancers
Koodie L,Robertson MG,Chandrashekar M,Ruth G,Dunning M,Bianco RW,Davydova J
MA5-12308 was used in Immunocytochemistry-Immunofluorescence to explore pigs as a model to study the performance of fiber-modified Adenovirus type 5/3 chimeric vectors.
Fri Feb 08 00:00:00 UTC 2019
Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts.
The Journal of clinical endocrinology and metabolism
Marlow LA,Rohl SD,Miller JL,Knauf JA,Fagin JA,Ryder M,Milosevic D,Netzel BC,Grebe SK,Reddi HV,Smallridge RC,Copland JA
MA5-12308 was used in Immunohistochemistry to create a standardised approach for cell line and patient-derived tumour xenograft characterisation to make valid preclinical models for thyroid cancer research.
Sat Sep 01 00:00:00 UTC 2018
Methodology, Criteria, and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts.
The Journal of clinical endocrinology and metabolism
Marlow LA,Rohl SD,Miller JL,Knauf JA,Fagin JA,Ryder M,Milosevic D,Netzel BC,Grebe SK,Reddi HV,Smallridge RC,Copland JA
MA5-12308 was used in Immunohistochemistry to create a standardised approach for cell line and patient-derived tumour xenograft characterisation to make valid preclinical models for thyroid cancer research.
Sat Sep 01 00:00:00 UTC 2018
Abstracts of the Endocrine Society of Australia's Annual Scientific Meeting 2017.
Clinical endocrinology
No authors listed
MA5-12308 was used in Immunohistochemistry to identifyand quantify biased agonism at class B GPCRs using the GLP-1R as the key exemplar and describe how we are now combining recent structural data with scanning mutagenesis to provide insights into the initiation and propagation of biased agonism.
Fri Jun 01 00:00:00 UTC 2018
Epigenetic Modifications in Thyroid Cancer Cells Restore NIS and Radio-Iodine Uptake and Promote Cell Death.
Journal of clinical medicine
Wächter S,Damanakis AI,Elxnat M,Roth S,Wunderlich A,Verburg FA,Fellinger SA,Bartsch DK,Di Fazio P
MA5-12308 was used in Western Blotting to show that H19 was differently expressed in human anaplastic, follicular and papillary thyroid tumor samples.
Wed Mar 21 00:00:00 UTC 2018
Selumetinib Activity in Thyroid Cancer Cells: Modulation of Sodium Iodide Symporter and Associated miRNAs.
International journal of molecular sciences
Wächter S,Wunderlich A,Greene BH,Roth S,Elxnat M,Fellinger SA,Verburg FA,Luster M,Bartsch DK,Di Fazio P
MA5-12308 was used in Western Blotting to analyse the effect of selumetinib on the expression of sodium iodide symporter and associated miRNAs in thyroid cancer cells.
Tue Jul 17 00:00:00 UTC 2018
Correlation of iodine symporter expression in highly and low malignant cell lines of human breast cancer differed in their sensitivity to doxorubicin.
Experimental oncology
Lukianova NY,Andriiv AV,Chekhun VF
MA512308 was used in immunocytochemistry to study the relationship between sodium/iodide symporter expression and human breast cancer cell lines with different sensitivity to doxorubicin
Thu Sep 01 00:00:00 UTC 2016
Upregulation of sodium iodide symporter (NIS) protein expression by an innate immunity component: Promising potential for targeting radiosensitive retinoblastoma.
Experimental eye research
Samuel J,Singh N,Kanwar JR,Krishnakumar S,Kanwar RK
MA5-12308 was used in western blot to discuss methods to treat retinoblastoma
Thu Oct 01 00:00:00 UTC 2015
Relations Between Pathological Markers and Radioiodine Scan and (18)F-FDG PET/CT Findings in Papillary Thyroid Cancer Patients With Recurrent Cervical Nodal Metastases.
Nuclear medicine and molecular imaging
Lee JW,Min HS,Lee SM,Kwon HW,Chung JK
MA5-12308 was used in Immunohistochemistry to investigate the relationships between immunohistochemical results and radioiodine scan and (18)F-FDG PET findings in papillary thyroid cancer patients with recurrent cervical nodal metastases.
Mon Jun 01 00:00:00 UTC 2015
Detailed assessment of gene activation levels by multiple hypoxia-responsive elements under various hypoxic conditions.
Annals of nuclear medicine
Takeuchi Y,Inubushi M,Jin YN,Murai C,Tsuji AB,Hata H,Kitagawa Y,Saga T
MA5-12308 was used in immunohistochemistry - paraffin section to assess gene activation under various hypoxic conditions in vivo.
Mon Dec 01 00:00:00 UTC 2014
Long-term effects of hepatocyte growth factor gene therapy in rat myocardial infarct model.
Gene therapy
Jin YN,Inubushi M,Masamoto K,Odaka K,Aoki I,Tsuji AB,Sagara M,Koizumi M,Saga T
MA5-12308 was used in western blot to investigate the therapeutic effect of hepatocyte growth factor gene transfer in a rat myocardial infarct model
Wed Aug 01 00:00:00 UTC 2012
Human sodium-iodide symporter (hNIS) gene expression is inhibited by a trans-active transcriptional repressor, NIS-repressor, containing PARP-1 in thyroid cancer cells.
Endocrine-related cancer
Li W,Ain KB
MA5-12308 was used in western blot to investigate the mechanism of human sodium-iodide symporter regulation in thyroid cancer cells
Tue Jun 01 00:00:00 UTC 2010
The pan-DAC inhibitor LBH589 is a multi-functional agent in breast cancer cells: cytotoxic drug and inducer of sodium-iodide symporter (NIS).
Breast cancer research and treatment
Fortunati N,Catalano MG,Marano F,Mugoni V,Pugliese M,Bosco O,Mainini F,Boccuzzi G
MA5-12308 was used in immunocytochemistry to investigate the effect of LBH589 on breast cancer cells and its mechanism
Wed Dec 01 00:00:00 UTC 2010
Immunoanalysis indicates that the sodium iodide symporter is not overexpressed in intracellular compartments in thyroid and breast cancers.
European journal of endocrinology
Peyrottes I,Navarro V,Ondo-Mendez A,Marcellin D,Bellanger L,Marsault R,Lindenthal S,Ettore F,Darcourt J,Pourcher T
MA5-12308 was used in western blot to study sodium iodide symporter expression in thyroid and breast cancers
Sun Feb 01 00:00:00 UTC 2009
Immunohistochemical expression of the human sodium/iodide symporter distinguishes malignant from benign gastric lesions.
International journal of surgical pathology
Farnedi A,Eusebi LH,Poli F,Foschini MP
MA5-12308 was used in immunohistochemistry to investigate the diagnostic value of sodium/iodide symporter expression in malignant and benign gastric lesions
Sat Aug 01 00:00:00 UTC 2009
Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Yeom CJ,Chung JK,Kang JH,Jeon YH,Kim KI,Jin YN,Lee YM,Jeong JM,Lee DS
MA5-12308 was used in western blot to examine the transcriptional activation of hypoxia-inducible factor-1 in C6 glioma
Mon Sep 01 00:00:00 UTC 2008
Targeting sodium/iodide symporter gene expression for estrogen-regulated imaging and therapy in breast cancer.
Cancer gene therapy
Montiel-Equihua CA,Martín-Duque P,de la Vieja A,Quintanilla M,Burnet J,Vassaux G,Lemoine NR
MA5-12308 was used in immunocytochemistry to study the use of adenovirus-expressed sodium iodide symporter for imaging and therapy of ER-positive breast tumors
Tue Jul 01 00:00:00 UTC 2008
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
Gastroenterology
Liu B,Hervé J,Bioulac-Sage P,Valogne Y,Roux J,Yilmaz F,Boisgard R,Guettier C,Calès P,Tavitian B,Samuel D,Clerc J,Bréchot C,Faivre J
MA5-12308 was used in immunohistochemistry to study the role of the sodium iodide symporter in human cholangiocarcinoma
Sun Apr 01 00:00:00 UTC 2007
SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene.
Gene therapy
Merron A,Peerlinck I,Martin-Duque P,Burnet J,Quintanilla M,Mather S,Hingorani M,Harrington K,Iggo R,Vassaux G
MA5-12308 was used in Immunohistochemistry to study the use of the human sodium iodide symporter as a reporter gene in wild-type and replication-selective adenoviruses.
Sat Dec 01 00:00:00 UTC 2007
A novel loss-of-function deletion in sodium/iodide symporter gene in follicular thyroid adenoma.
Cancer letters
Liang JA,Chen CP,Huang SJ,Ho TY,Hsiang CY,Ding HJ,Wu SL
MA5-12308 was used in western blot to study the sodium/iodide symporter gene mutation in follicular thyroid adenoma
Thu Dec 08 00:00:00 UTC 2005
