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产品信息
H00006531-D01P
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SLC6A3 (NP_001035.1, 1 a.a. approximately 620 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSKSKCSVGL MSSVVAPAKE PNAVGPKEVE LILVKEQNGV QLTSSTLTNP RQSPVEAQDR ETWGKKIDFL LSVIGFAVDL ANVWRFPYLC YKNGGGAFLV PYLLFMVIAG MPLFYMELAL GQFNREGAAG VWKICPILKG VGFTVILISL YVGFFYNVII AWALHYLFSS FTTELPWIHC NNSWNSPNCS DAHPGDSSGD SSGLNDTFGT TPAAEYFERG VLHLHQSHGI DDLGPPRWQL TACLVLVIVL LYFSLWKGVK TSGKVVWITA TMPYVVLTAL LLRGVTLPGA IDGIRAYLSV DFYRLCEASV WIDAATQVCF SLGVGFGVLI AFSSYNKFTN NCYRDAIVTT SINSLTSFSS GFVVFSFLGY MAQKHSVPIG DVAKDGPGLI FIIYPEAIAT LPLSSAWAVV FFIMLLTLGI DSAMGGMESV ITGLIDEFQL LHRHRELFTL FIVLATFLLS LFCVTNGGIY VFTLLDHFAA GTSILFGVLI EAIGVAWFYG VGQFSDDIQQ MTGQRPSLYW RLCWKLVSPC FLLFVVVVSI VTFRPPHYGA YIFPDWANAL GWVIATSSMA MVPIYAAYKF CSLPGSFREK LAYAIAPEKD RELVDRGEVR QFTLRHWLKV
靶标信息
The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DA transporter; DAT; dopamine transporter 1; Sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Solute carrier family 6 member 3; solute carrier family 6, member 3
基因别名: DAT; DAT1; PKDYS; SLC6A3
UniProt ID: (Human) Q01959, (Rat) P23977
Entrez Gene ID: (Human) 6531, (Rat) 24898
protease binding
receptor binding
dopamine transmembrane transporter activity
dopamine:sodium symporter activity
protein binding
drug binding
monoamine transmembrane transporter activity
protein complex binding
dopamine binding
metal ion binding
protein N-terminus binding
protein phosphatase 2A binding
primary active transporter
aging
lactation
sensory perception of smell
locomotory behavior
response to iron ion
monoamine transport
dopamine transport
adenohypophysis development
response to nicotine
positive regulation of multicellular organism growth
regulation of dopamine metabolic process
neurotransmitter biosynthetic process
response to cocaine
dopamine biosynthetic process
dopamine catabolic process
response to drug
response to ethanol
dopamine uptake involved in synaptic transmission
response to cAMP
prepulse inhibition
ammonium transmembrane transport
dopamine uptake
neurotransmitter transport
response to organic cyclic compound
cation transmembrane transport
