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SLC7A11 Antibody (PA5-18599) in ICC/IF
Immunocytochemistry analysis of SLC7A11 using SLC7A11 Polyclonal Antibody (Product # PA5-18599) in paraformaldehyde fixed A549 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing vesicle/ER staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
产品信息
PA5-18599
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KGQTQNFKDAFSGRD) corresponding to the internal amino acids of SLC7A11
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10986113
产品详细信息
This antibody is predicted to react with canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Cystine/glutamate transporter; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; Solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT
基因别名: CCBR1; SLC7A11; xCT
UniProt ID: (Human) Q9UPY5
Entrez Gene ID: (Human) 23657
