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Antibody detects endogenous levels of total SLCO1C1.
This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: OAT-RP-5; OATP-14; OATP-F; OATP1C1; Organic anion transporter 1C1; Organic anion transporter F; Organic anion transporter polypeptide-related protein 5; organic anion transporting polypeptide 14; Organic anion-transporting polypeptide 14; solute carrier family 21 (organic anion transporter), member 14; Solute carrier family 21 member 14; Solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family, member 1C1; Thyroxine transporter
基因别名: OATP-F; OATP1; OATP14; OATP1C1; OATPF; OATPRP5; SLC21A14; SLCO1C1
UniProt ID: (Human) Q9NYB5
Entrez Gene ID: (Human) 53919
分子生物学功能: transporter