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产品信息
13835-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SLITRK4 Fusion Protein Ag4781 (33-355 aa encoded by BC040986)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VSVENVLYV NCEKVSVYRP NQLKPPWSNF YHLNFQNNFL NILYPNTFLN FSHAVSLHLG NNKLQNIEGG AFLGLSALKQ LHLNNNELKI LRADTFLGIE NLEYLQADYN LIKYIERGAF NKLHKLKVLI LNDNLISFLP DNIFRFASLT HLDIRGNRIQ KLPYIGVLEH IGRVVELQLE DNPWNCSCDL LPLKAWLENM PYNIYIGEAI CETPSDLYGR LLKETNKQEL CPMGTGSDFD VRILPPSQLE NGYTTPNGHT TQTSLHRLVT KPPKTTNPSK ISGIVAGKAL SNRNLSQIVS YQTRVPPLTP CPAPCFCKTH PSDL (33-355 aa encoded by BC040986)
靶标信息
SLIT and NTRK-like family 4 (Slitrk4) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk4 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: SLIT and NTRK-like family, member 4; SLIT and NTRK-like protein 4; slit and trk like gene 4
基因别名: 6430513G13; D930039I09Rik; SLITRK4
UniProt ID: (Human) Q8IW52, (Mouse) Q810B8
Entrez Gene ID: (Human) 139065, (Mouse) 245446, (Rat) 302473
