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产品信息
H00006604-M04
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
5B6
抗原
SMARCD3 (NP_001003801, 385 a.a. approximately 483 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: ISALDSKIHE TIESINQLKI QRDFMLSFSR DPKGYVQDLL RSQSRDLKVM TDVAGNPEEE RRAEFYHQPW SQEAVSRYFY CKIQQRRQEL EQSLVVRNT
靶标信息
BAF60C is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 60 kDa BRG-1/Brm-associated factor subunit C; BAF60C; BRG1-associated factor 60C; chromatin remodeling complex BAF60C subunit; mammalian chromatin remodeling complex BRG1-associated factor 60C; mBAF60c; MGC111010; SWI/SNF complex 60 kDa subunit C; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, isoform 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Swp73-like protein
基因别名: 1500001J14Rik; 2210409C08Rik; BAF60C; CRACD3; Rsc6p; SMARCD3
UniProt ID: (Human) Q6STE5, (Mouse) Q6P9Z1
Entrez Gene ID: (Human) 6604, (Mouse) 66993, (Rat) 296732
chromatin binding
transcription coactivator activity
receptor binding
transcription factor binding
nuclear hormone receptor binding
protein binding
ligand-dependent nuclear receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
chromatin/chromatin-binding, or -regulatory protein
positive regulation of neuroblast proliferation
secondary heart field specification
cardiac right ventricle formation
neural retina development
nucleosome disassembly
chromatin remodeling
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of G2/M transition of mitotic cell cycle
covalent chromatin modification
muscle cell differentiation
regulation of protein binding
cellular lipid metabolic process
positive regulation of transcription, DNA-templated
positive regulation of smooth muscle cell differentiation
heart morphogenesis
regulation of transcription, DNA-templated
nervous system development
chromatin modification
