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产品信息
PA5-69826
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide corresponding to a region of mouse SMPDL3A (aa 82-131).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2689857
产品详细信息
This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
靶标信息
Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 2',3'-cGAMP phosphodiesterase SMPDL3A; Acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; Cyclic GMP-AMP phosphodiesterase SMPDL3A
基因别名: 0610010C24Rik; AI529588; ASM3A; ASML3; ASML3A; Smpdl3a
UniProt ID: (Mouse) P70158
Entrez Gene ID: (Mouse) 57319
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
photoreceptor cyclic-nucleotide phosphodiesterase activity
sphingomyelin phosphodiesterase activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity
inositol phosphosphingolipid phospholipase activity
inositol phosphorylceramide phospholipase activity
mannosyl-inositol phosphorylceramide phospholipase activity
mannosyl-diinositol phosphorylceramide phospholipase activity
hydrolase
phosphodiesterase
metabolite interconversion enzyme
