Search Thermo Fisher Scientific
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human SMPDL3A.
Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 0610010C24Rik; 2',3'-cGAMP phosphodiesterase SMPDL3A; Acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; Cyclic GMP-AMP phosphodiesterase SMPDL3A; sphingomyelin phosphodiesterase acid-like 3A; sphingomyelin phosphodiesterase, acid-like 3A
基因别名: ASM3A; ASML3A; SMPDL3A; yR36GH4.1
UniProt ID: (Human) Q92484
Entrez Gene ID: (Human) 10924