Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
23875-1-AP
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SNRNP200 Fusion Protein Ag20748 (1787-2136 aa encoded by BC001417)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ELVEQTLSD LEQSKCISIE DEMDVAPLNL GMIAAYYYIN YTTIELFSMS LNAKTKVRGL IEIISNAAEY ENIPIRHHED NLLRQLAQKV PHKLNNPKFN DPHVKTNLLL QAHLSRMQLS AELQSDTEEI LSKAIRLIQA CVDVLSSNGW LSPALAAMEL AQMVTQAMWS KDSYLKQLPH FTSEHIKRCT DKGVESVFDI MEMEDEERNA LLQLTDSQIA DVARFCNRYP NIELSYEVVD KDSIRSGGPV VVLVQLEREE EVTGPVIAPL FPQKREEGWW VVIGDAKSNS LISIKRLTLQ QKAKVKLDFV APATGAHNYT LYFMSDAYMG CDQEYKFSVD VKEAETDSDS D (1787-2136 aa encoded by BC001417)
靶标信息
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Activating signal cointegrator 1 complex subunit 3-like 1; bad response to refrigeration 2 homolog; BRR2 homolog; small nuclear ribonucleoprotein 200kDa (U5); small nuclear ribonucleoprotein, U5 200kDa subunit; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP-specific 200 kDa protein; U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family); U5-200KD
基因别名: A330064G03Rik; ASCC3L1; BC011390; BRR2; HELIC2; KIAA0788; RP33; SNRNP200; U5-200-KD; U5-200KD
UniProt ID: (Human) O75643, (Mouse) Q6P4T2
Entrez Gene ID: (Human) 23020, (Mouse) 320632
