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SNX1 Antibody (H00006642-D01P) in WB
Western Blot analysis of SNX1 expression in transfected 293T cell line (H00006642-T03) by SNX1 MaxPab polyclonal antibody.
Lane 1: SNX1 transfected lysate(59.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: SNX1 transfected lysate(59.10 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00006642-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SNX1 (NP_003090.2, 1 a.a. approximately 522 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MASGGGGCSA SERLPPPFPG LEPESEGAAG GSEPEAGDSD TEGEDIFTGA AVVSKHQSPK ITTSLLPINN GSKENGIHEE QDQEPQDLFA DATVELSLDS TQNNQKKVLA KTLISLPPQE ATNSSKPQPT YEELEEEEQE DQFDLTVGIT DPEKIGDGMN AYVAYKVTTQ TSLPLFRSKQ FAVKRRFSDF LGLYEKLSEK HSQNGFIVPP PPEKSLIGMT KVKVGKEDSS SAEFLEKRRA ALERYLQRIV NHPTMLQDPD VREFLEKEEL PRAVGTQTLS GAGLLKMFNK ATDAVSKMTI KMNESDIWFE EKLQEVECEE QRLRKLHAVV ETLVNHRKEL ALNTAQFAKS LAMLGSSEDN TALSRALSQL AEVEEKIEQL HQEQANNDFF LLAELLSDYI RLLAIVRAAF DQRMKTWQRW QDAQATLQKK REAEARLLWA NKPDKLQQAK DEILEWESRV TQYERDFERI STVVRKEVIR FEKEKSKDFK NHVIKYLETL LYSQQQLAKY WEAFLPEAKA IS
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC8664; SNX1A; sorting nexin 1A; Sorting nexin-1
基因别名: HsT17379; SNX1; VPS5
UniProt ID: (Human) Q13596
Entrez Gene ID: (Human) 6642
epidermal growth factor receptor binding
insulin receptor binding
protein binding
phosphatidylinositol binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
cadherin binding involved in cell-cell adhesion
transferrin receptor binding
leptin receptor binding
scaffold/adaptor protein
