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SNX9 Antibody (PA5-119807) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human placenta tissue using SNX9 Polyclonal Antibody (Product # PA5-119807). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the SNX9 antibody at a dilution of ... View More
产品信息
PA5-119807
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within human SH3PX1 aa 430-595
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2913379
产品详细信息
Positive Control: Hela cell lysate, 293T cell lysate, NIH/3T3 cell lysate, mouse heart tissue lysate, rat smooth muscle tissue lysate, rat uterus tissue, human placenta tissue, mouse testis tissue.
Subcellular Location: Trans-Golgi network, Cell membrane, Cytoplasmic vesicle membrane, Clathrin-coated vesicle, Ruffle, Cytoplasm.
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MST155; MSTP155; OTTHUMP00000040083; Protein SDP1; RP11-266C7.10; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Sorting nexin-9; Wiskott-Aldrich syndrome protein (WASP) interactor protein
基因别名: 2700073N08Rik; SDP1; SH3PX1; SH3PXD3A; SNX9; WISP
UniProt ID: (Human) Q9Y5X1, (Mouse) Q91VH2
Entrez Gene ID: (Human) 51429, (Mouse) 66616, (Rat) 683687
mitotic cytokinesis
intracellular protein transport
endocytosis
receptor-mediated endocytosis
mitotic nuclear division
vesicle organization
endosomal transport
positive regulation of protein oligomerization
cleavage furrow formation
positive regulation of GTPase activity
positive regulation of protein kinase activity
positive regulation of membrane protein ectodomain proteolysis
lipid tube assembly
membrane tubulation
cell-cell adhesion
transport
cell cycle
protein transport
cell division
