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Antibody detects endogenous levels of total SOD3.
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ALS1; EC SOD; EC-SOD; extracellular superoxide dismutase; Extracellular superoxide dismutase [Cu-Zn]; MGC20077; SOD 3; Superoxide dimutase 3; superoxide dismutase; Superoxide dismutase B; testicular tissue protein Li 175
基因别名: AI314465; EC-SOD; ECSODPT; Sod-3; SOD3
UniProt ID: (Human) P08294, (Rat) Q08420, (Mouse) O09164
Entrez Gene ID: (Human) 6649, (Rat) 25352, (Mouse) 20657