Search Thermo Fisher Scientific
Immunogen sequence: LDCSALDRDPD LQPPSGTSHF EFPD
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein SOX-22; SOX-22 protein; SRY (sex determining region Y)-box 12; SRY box 12; SRY-related HMG-box gene 22; Transcription factor SOX-12
基因别名: SOX12; SOX22
UniProt ID: (Human) O15370
Entrez Gene ID: (Human) 6666