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Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, human brain
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SRY (sex determining region Y)-box 8; SRY box 8; Transcription factor SOX-8
基因别名: SOX8
UniProt ID: (Human) P57073
Entrez Gene ID: (Human) 30812