Invitrogen

SPR Polyclonal Antibody

产品信息

PA5-58819

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:2,500-1:5,000

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SPR. Recombinant protein control fragment (Product #RP-97605).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.9 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2647886

产品详细信息

Immunogen sequence: LEEPNVRVLN YAPGPLDTDM QQLARETSVD PDMRKGLQEL KAKGKLVDCK VSAQKLLSLL EKDEFKSGAH VDFY

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 73%.

靶标信息

SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。