Invitrogen

SR-BI Recombinant Rabbit Monoclonal Antibody (SR37-06)

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他17个SR-BI抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (7)
高级验证 (1)

SR-BI Antibody in Immunocytochemistry (ICC/IF)

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SR-BI Antibody (MA5-32001) in ICC/IF

Immunocytochemical analysis of SR-BI in PC-12 cells using a SR-BI Monoclonal antibody (Product # MA5-32001) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

SR-BI Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SR-BI Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across the cell lines and tissues tested owing to their inherent genetic constitution. Relative expression of SCARB1 was observed in HeLa, Hep G2, PC3 in comparison to Jurkat and MOLT-4 and in Mouse Ovary, Mouse Adrenal, Mouse Liver, Rat Liver as compared to Mouse Brain and Mouse Kidney using Anti-SR-BI Recombinant Rabbit Monoclonal Antibody (SR37-06) (Product # MA5-32001) in Western Blot. {RE}

产品信息

MA5-32001

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

SR37-06

抗原

Synthetic peptide within Human SRB1 aa 81-130

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2809295

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen-like 1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; HDL QTL 1; scavanger receptor class B type 1; scavenger receptor b1; Scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SR-BI; SRB1

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基因别名: AI120173; CD36; CD36L1; CLA-1; CLA1; D5Ertd460e; Hdlq1; HDLQTL6; Hlb398; mSR-BI; SCARB1; SR-B1; SR-BI; SRB1; SRBI

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UniProt ID: (Human) Q8WTV0, (Rat) P97943, (Mouse) D3Z2V4

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Entrez Gene ID: (Human) 949, (Rat) 25073, (Mouse) 20778

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