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Invitrogen

SRC1 Recombinant Rabbit Monoclonal Antibody (3S4C6)

查看其他10个SRC1抗体
说明书
实验方案
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说明书
实验方案
技术支持

产品信息

MA5-42905

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
-

酶联免疫吸附实验 (ELISA)

1 µg/mL
-

免疫沉淀 (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of
-
产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

3S4C6

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human KAT13A / SRC1 (Q15788).
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偶联物

Unconjugated

形式

Liquid

浓度

1.55 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2912046

产品详细信息

Positive test controls include: HeLa, 293T, SGC-7901.

Immunogen sequence: VARSSTLPPS NSNMVSTRIN RQQSSDLHSS SHSNSSNSQG SFGCSPGSQI VANVALNQGQ ASSQSSNPSL NLNNSPMEGT GISLAQFMSP RRQVTSGLAT RPRMPNNSFP PNISTLSSPV GMTSSACNNN NRSYSNIPVT SLQGMNEGPN NSVGFSASSP VLRQMSSQNS PSRLNIQPAK AESKDNKEIA SILNEMIQSD NSSSDGKPLD SGLLHNNDRL SDGDSKYSQT SHKLVQLLTT TAEQQLRHAD IDTSCKDVLS CTGTSNSASA NSSGGSCPSS HSSLTERHKI LHRLLQEGSP SDITTLSVEP DKKDSASTSV SVTGQVQGNS SIKLELDASK KKESKDHQLL R

靶标信息

Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ASV; bHLHe74; c-SRC; Class E basic helix-loop-helix protein 74; Hin-2 protein; NCoA-1; Nuclear receptor coactivator 1; p60-Src; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; SRC-1; SRC-1 (-Q); Steroid receptor coactivator 1; steroid receptor coactivator-1

基因别名: bHLHe42; BHLHE74; F-SRC-1; KAT13A; NCOA1; RIP160; SRC1

UniProt ID: (Human) Q15788

Entrez Gene ID: (Human) 8648

功能
RNA polymerase II regulatory region DNA binding RNA polymerase II transcription coactivator activity chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding ligand-dependent nuclear receptor binding enzyme binding estrogen receptor binding ligand-dependent nuclear receptor transcription coactivator activity protein complex binding progesterone receptor binding nuclear hormone receptor binding retinoid X receptor binding protein dimerization activity protein N-terminus binding androgen receptor binding histone modifying enzyme
参与通路
positive regulation of transcription from RNA polymerase II promoter by galactose regulation of thyroid hormone mediated signaling pathway transcription, DNA-templated lactation male gonad development bile acid and bile salt transport cerebellum development hippocampus development hypothalamus development cerebral cortex development androgen receptor signaling pathway intracellular receptor signaling pathway response to estradiol response to retinoic acid response to progesterone cellular response to hormone stimulus positive regulation of apoptotic process histone H4 acetylation cellular lipid metabolic process estrous cycle positive regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of female receptivity positive regulation of transcription from RNA polymerase II promoter male mating behavior labyrinthine layer morphogenesis cellular response to Thyroglobulin triiodothyronine regulation of cellular response to drug
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