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SRSF2 Antibody (PA5-92037) in IHC (P)
Immunohistochemistry analysis of SRSF2 in paraffin-embedded human lung. Samples were incubated with SRSF2 Polyclonal antibody (Product # PA5-92037) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-92037
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF2 (NP_0011823561)
偶联物
形式
Liquid
浓度
2.42 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806360
产品详细信息
Immunogen sequence: MSYGRPPPDV EGMTSLKVDN LTYRTSPDTL RRVFEKYGRV GDVYIPRDRY TKESRGFAFV RFHDKRDAED AMDAMDGAVL DGRELRVQMA RYGRPPDSHH
Positive Samples: Mouse lung; Cellular Location: Nucleus, Nucleus speckle, nucleoplasm
靶标信息
The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for SC35. In addition, a pseudogene of SC35 has been found on chromosome 11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MRF-1; myelin regulatory factor 1; Protein PR264; Putative myelin regulatory factor 1; SC-35; Serine/arginine-rich splicing factor 2; Splicing component, 35 kDa; Splicing factor SC35; Splicing factor, arginine/serine-rich 2; splicing factor, arginine/serine-rich 2 (SC-35); SR splicing factor 2
基因别名: D11Wsu175e; MRF-1; PR264; SC-35; SC35; Sfrs10; SFRS2; SFRS2A; SRp30b; SRSF2
UniProt ID: (Human) Q01130, (Mouse) Q62093, (Rat) Q6PDU1
Entrez Gene ID: (Human) 6427, (Mouse) 20382, (Rat) 494445
