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It is not recommended to aliquot this antibody.
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: autoantigen La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family, member 3; lupus La antigen; Lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); mRNA for autoantigen; OTTHUMP00000204777; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); SS-B; SS-B/La protein
基因别名: La; La/SSB; LARP3; SS-B; SSB
UniProt ID: (Human) P05455, (Mouse) P32067
Entrez Gene ID: (Human) 6741, (Rat) 81783, (Mouse) 20823
分子生物学功能:
RNA metabolism protein