Invitrogen

SSTR5 Recombinant Rabbit Monoclonal Antibody (19H17L5)

SSTR5 Antibody in Immunocytochemistry (ICC/IF)

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SSTR5 Antibody (704013) in ICC/IF

HEK-293 cells stably transfected with SSTR5 were grown on poly-L-lysine-coated coverslips overnight. After 24 h, cells were fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with SSTR5 Recombinant Rabbit Monoclonal Antibody (Product # 704013, 1:500 dilution). Cells were then incubated with Alexa488-conjugated secondary antibody for 2 h at room temperature, mount... View More

SSTR5 Antibody in Immunohistochemistry (IHC)

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产品信息

704013

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500

免疫组化 (IHC)

1:500

免疫细胞化学 (ICC/IF)

1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Monoclonal

类型

Antibody

克隆号

19H17L5

抗原

Peptides corresponding to residues 344-364 of Human SSTR5

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2895897

靶标信息

Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

仅用于科研。不用于诊断过程。未经明确授权不得转售。