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STAP1 Antibody (630-820) in IHC (P)
Immunohistochemistry: Human Tonsil (FFPE) stained with Rabbit anti-STAP1 antibody (Cat# 630-820) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
产品信息
630-820
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide LHE VLE REK KRR IET derived from human STAP1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with proprietary stabilizer
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: Tonsil
Cellular location: Nucleus and cytoplasm.
靶标信息
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCR downstream signaling 1; BCR downstream-signaling protein 1; Docking protein BRDG1; Signal-transducing adaptor protein 1; STAP-1; Stem cell adaptor protein 1; stem cell adaptor protein STAP-1
基因别名: AI586015; BRDG1; RGD1311584; STAP-1; STAP1
UniProt ID: (Human) Q9ULZ2, (Mouse) Q9JM90
Entrez Gene ID: (Human) 26228, (Rat) 305269, (Mouse) 56792
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of gene expression
negative regulation of macrophage chemotaxis
negative regulation of phosphorylation
positive regulation of B cell receptor signaling pathway
positive regulation of phagocytosis, engulfment
cellular response to lipopolysaccharide
negative regulation of ruffle assembly
negative regulation of macrophage colony-stimulating factor signaling pathway
positive regulation of microglial cell activation
positive regulation of non-membrane spanning protein tyrosine kinase activity
negative regulation of microglial cell migration
positive regulation of microglial cell mediated cytotoxicity
positive regulation of actin cytoskeleton reorganization
positive regulation of signal transduction
myeloid cell differentiation
