Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 2
SYNE3 Antibody (MA5-55501) in WB
Western Blot analysis of various lysates using SYNE3 Recombinant Monoclonal Antibody (Product # MA5-55501) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
MA5-55501
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5P10J3
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 750-935 of human Nesprin3.
偶联物
Unconjugated
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
产品详细信息
Immunogen Sequence: LIRNWHLQRM EVDSGKKMVF TNNIPKSGFL INPMDPIPRH RRRANLLQEE EGSHEDFSQL LRNFGQWLQV ENSKLVRIIA MRTSTAEDLR TRKSKLQELE ARVPEGQHLF ENLLRLGPAR GTSDELEDLR YQWMLYKSKL KDSGHLLTQS SPGEPTGFQK TRRWRGLGSL FRRACCVALP LQLLLL
靶标信息
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: KASH domain-containing protein 3; KASH3; Nesprin-3; Nuclear envelope spectrin repeat protein 3; spectrin repeat containing, nuclear envelope family member 3
基因别名: C14orf139; C14orf49; LINC00341; Nesp3; nesprin-3; NET53; SYNE3
UniProt ID: (Human) Q6ZMZ3, (Mouse) Q4FZC9
Entrez Gene ID: (Human) 161176, (Mouse) 212073
