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This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Synaptotagmin XII; Synaptotagmin-12; synaptotagmin-XII; Synaptotagmin12; SynaptotagminXII; Syt XII; SYT-12; SytXII
基因别名: SYT11; SYT12; sytXII
UniProt ID: (Human) Q8IV01
Entrez Gene ID: (Human) 91683