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Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: calcium channel, voltage-dependent, gamma subunit 2; CaV gamma 2; MGC123981; MGC138502; MGC138504; Neuronal voltage-gated calcium channel gamma-2 subunit; Stargazin; TARP gamma 2; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; Voltage-dependent calcium channel gamma-2 subunit
基因别名: AW060990; B230105C07Rik; B930041E13Rik; CACNG2; Ipr328; MRD10; stargazer; stargazin; Stg; wag; waggler
UniProt ID: (Human) Q9Y698, (Rat) Q71RJ2, (Mouse) O88602
Entrez Gene ID: (Human) 10369, (Rat) 84347, (Mouse) 12300