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Stathmin 1 Antibody (PA5-120796) in IHC (P)
Immunohistochemistry analysis of Stathmin 1 in paraffin-embedded rat brain. Samples were incubated with Stathmin 1 Polyclonal antibody (Product # PA5-120796) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-120796
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Stathmin 1 (NP_0055541)
偶联物
形式
Liquid
浓度
2.62 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914368
产品详细信息
Positive test controls include: SW620, Mouse thymus, Rat thymus. The target is usually found in the following locations: Cytoplasm, cytoskeleton.
Immunogen sequence: MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK
靶标信息
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; Leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; Stathmin; stathmin 1 variant; stathmin 1/oncoprotein 18; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
基因别名: 19k; C1orf215; Lag; LAP18; OP18; P18; P19; Pig; PP17; Pp18; PP19; PR22; prosolin; SMN; STMN1
UniProt ID: (Human) P16949, (Rat) P13668, (Mouse) P54227
Entrez Gene ID: (Human) 3925, (Rat) 29332, (Mouse) 16765
microtubule depolymerization
mitotic spindle organization
axonogenesis
brain development
response to virus
regulation of microtubule polymerization or depolymerization
negative regulation of microtubule polymerization
neuron projection development
intracellular signal transduction
positive regulation of cellular component movement
regulation of cytoskeleton organization
mitotic cytokinesis
signal transduction
multicellular organism development
nervous system development
cell differentiation
