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Stathmin 1 Antibody (PA5-89578) in WB
Western blot analysis of Stathmin 1 in extracts of various cell lines. Samples were incubated with Stathmin 1 Polyclonal antibody (Product # PA5-89578) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.
产品信息
PA5-89578
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-149 of human Stathmin 1 (NP_9819441)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805664
产品详细信息
Immunogen sequence: MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL ERLREKDKHI EEVRKNKESK DPADETEAD; Positive Samples: SW620, U-937, Jurkat; Cellular Location: Cytoplasm, cytoskeleton
靶标信息
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leukemia associated phosphoprotein p18; Leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Prosolin; Protein Pr22; RP1-125I3.5; Stathmin; stathmin 1 variant; stathmin 1/oncoprotein 18; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
基因别名: 19k; C1orf215; Lag; LAP18; OP18; P18; P19; Pig; PP17; Pp18; PP19; PR22; SMN; STMN1
UniProt ID: (Human) P16949, (Mouse) P54227
Entrez Gene ID: (Human) 3925, (Mouse) 16765
mitotic cytokinesis
microtubule depolymerization
mitotic spindle organization
signal transduction
axonogenesis
brain development
response to virus
negative regulation of microtubule polymerization
neuron projection development
intracellular signal transduction
positive regulation of cellular component movement
regulation of cytoskeleton organization
multicellular organism development
nervous system development
cell differentiation
regulation of microtubule polymerization or depolymerization
