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Invitrogen
Stathmin 1 Monoclonal Antibody (SP49)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 6
Stathmin 1 Antibody (MA5-16400) in ICC/IF
Immunofluorescence analysis of Stathmin 1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Stathmin 1 Monoclonal Antibody (SP49) (Product # MA5-16400) at 1:100 dilution in 0.1% BSA, incubated at 4 de... View More
产品信息
MA5-16400
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
SP49
抗原
Synthetic peptide derived from the internal region of human stathmin
偶联物
形式
Liquid
纯化类型
Protein A/G
保存液
PBS, pH 7.6, with 1% BSA
内含物
0.1% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2537919
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil or breast carcinoma.
靶标信息
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; Leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; Stathmin; stathmin 1 variant; stathmin 1/oncoprotein 18; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
基因别名: 19k; C1orf215; Lag; LAP18; OP18; P18; P19; Pig; PP17; Pp18; PP19; PR22; prosolin; SMN; STMN1
UniProt ID: (Human) P16949, (Rat) P13668, (Mouse) P54227
Entrez Gene ID: (Human) 3925, (Rat) 29332, (Mouse) 16765
microtubule depolymerization
mitotic spindle organization
axonogenesis
brain development
response to virus
regulation of microtubule polymerization or depolymerization
negative regulation of microtubule polymerization
neuron projection development
intracellular signal transduction
positive regulation of cellular component movement
regulation of cytoskeleton organization
mitotic cytokinesis
signal transduction
multicellular organism development
nervous system development
cell differentiation
