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The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: inositol phosphate 5'-phosphatase 2; inositol polyphosphate-5-phosphatase H; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2; Synaptojanin-2
基因别名: AI481647; INPP5H; KIAA0348; mKIAA0348; SJ2; SYNJ2
UniProt ID: (Human) O15056, (Mouse) Q9D2G5, (Rat) O55207
Entrez Gene ID: (Human) 8871, (Mouse) 20975, (Rat) 84018
分子生物学功能: phosphatase