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Immunogen sequence: MDRLGPFSNDP SDKPPCRGCS SYLMEPYIKC AECGPPPFFL CLQCFTRGFE YKKHQSDHTY EIMTSD
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 99%.
TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as 2 alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling. Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. The gene that encodes TADA2L contains 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADA2-like protein; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; transcriptional adaptor 2 alpha
基因别名: ADA2; ADA2A; hADA2; KL04P; TADA2A; TADA2L
UniProt ID: (Human) O75478
Entrez Gene ID: (Human) 6871