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产品信息
10544-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TAF9 Fusion Protein Ag0833 (1-172 aa encoded by BC007426)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MLLPNILLT GTPGVGKTTL GKELASKSGL KYINVGDLAR EEQLYDGYDE EYDCPILDED RVVDELDNQM REGGVIVDYH GCDFFPERWF HIVFVLRTDT NVLYERLETR GYNEKKLTDN IQCEIFQVLY EEATASYKEE IVHQLPSNKP EELENNVDQI LKWIEQWIKD HNS (1-172 aa encoded by BC007426)
靶标信息
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AD-004; CGI-137; MGC:1603; MGC:3647; RNA polymerase II TBP-associated factor subunit G; STAF31/32; TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32 kDa; TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa; TAF9 RNA polymerase II, TATA box binding protein-associated factor; taf9 {ECO:0000312|EMBL:AAH91109.1}; TAFII-31; TAFII-32; TATA box binding protein associated factor 9; transcription initiation factor TFIID 31 kD subunit; Transcription initiation factor TFIID 31 kDa subunit; Transcription initiation factor TFIID 32 kDa subunit; Transcription initiation factor TFIID subunit 9
基因别名: 2310012M09Rik; AA673500; AU045423; CINAP; MGC:5067; STAF31/32; TAF2G; TAF9; TAFII-31; TAFII-32; TAFII31; TAFII32; TAFIID32
UniProt ID: (Human) Q16594, (Rat) Q5BKE0, (Mouse) Q8VI33
Entrez Gene ID: (Human) 6880, (Rat) 373541, (Mouse) 108143
p53 binding
DNA binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
activating transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity
ATPase binding
C2H2 zinc finger domain binding
chromatin/chromatin-binding, or -regulatory protein
box C/D snoRNP assembly
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
cellular response to DNA damage stimulus
positive regulation of cell growth
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
snRNA transcription from RNA polymerase II promoter
negative regulation of apoptotic process
histone H3 acetylation
positive regulation of transcription from RNA polymerase II promoter
protein stabilization
positive regulation of response to cytokine stimulus
response to interleukin-1
regulation of signal transduction by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
DNA-templated transcription, initiation
response to L-glutamate
