Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-37460
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 570-620 of human TAUT
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2554074
产品详细信息
This antibody detects endogenous protein at a molecular weight of 70 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNF alpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: MGC10619; MGC131729; OTTHUMP00000208177; OTTHUMP00000208180; SC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier 6 ,member 6 (taurine transporter); solute carrier family 6 (neurotransmitter transporter, taurine), member 6; Solute carrier family 6 member 6; solute carrier family 6, member 6; Taurine Transporter; taurine/beta-alanine transporter
基因别名: AA589629; C80501; SLC6A6; TAUT
UniProt ID: (Human) P31641, (Mouse) O35316, (Rat) P31643
Entrez Gene ID: (Human) 6533, (Mouse) 21366, (Rat) 29464
