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TAX1BP1 Antibody (702840) in ICC/IF
For immunofluorescence analysis, HeLa cells were fixed and permeabilized for detection of endogenous TAX1BP1 using Anti- TAX1BP1 Recombinant Rabbit Monoclonal Antibody (Product # 702840, 1:100 dilution) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000 dilution). Panel a) shows representative cells that were stained for detection and localization of TAX1BP1 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant wit... View More
产品信息
702840
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4H2L18
抗原
Protein corresponding to human TAX1BP1 [aa406-aa541]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2725478
产品详细信息
This antibody is predicted to react with Monkey, Dog, Horse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1-binding protein 1; Tax1-binding protein 1 homolog; TRAF6-binding protein; TRAF6-binding protein homolog
基因别名: 1200003J11Rik; 1700069J21Rik; AA930106; CALCOCO3; D6Ertd404e; D6Ertd772e; PRO0105; T6BP; TAX1BP1; TXBP151
UniProt ID: (Human) Q86VP1, (Mouse) Q3UKC1
Entrez Gene ID: (Human) 8887, (Mouse) 52440
