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TAZ Antibody (PA5-114792) in IHC (P)
Immunohistochemistry analysis of TAZ in mouse muscle tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114792) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
产品信息
PA5-114792
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TAZ(Accession Q16635), corresponding to amino acid residues G124-W174.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2899428
产品详细信息
Antibody detects endogenous levels of total TAZ.
靶标信息
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Barth syndrome); cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; FLJ27390; HGNC:11577; OTTHUMP00000061673; Protein G4.5; Tafazzin; tafazzin (cardiomyopathy, dilated 3A (X-linked); tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome); Taz; XX-FW83563B9.3
基因别名: 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAFAZZIN; TAZ; Taz1
UniProt ID: (Human) Q16635, (Mouse) Q91WF0
Entrez Gene ID: (Human) 6901, (Rat) 363521, (Mouse) 66826
muscle contraction
heart development
skeletal muscle tissue development
hemopoiesis
cardiolipin biosynthetic process
mitochondrial respiratory chain complex I assembly
cardiolipin acyl-chain remodeling
cristae formation
mitochondrial ATP synthesis coupled electron transport
cardiac muscle tissue development
cardiac muscle contraction
inner mitochondrial membrane organization
biological_process
phosphatidylglycerol metabolic process
