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Antibody detects endogenous levels of total TBC1D2.
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Armus; BC1D2; PARIS-1; Prostate antigen recognized and identified by SEREX 1; TBC1 domain family member 2A; TBC1 domain family, member 2; TBC1 domain family, member 2A
基因别名: PARIS-1; PARIS1; PP8997; TBC1D2; TBC1D2A
UniProt ID: (Human) Q9BYX2
Entrez Gene ID: (Human) 55357, (Rat) 313234
分子生物学功能: GTPase-activating protein