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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: T-box brain protein 1; T-brain-1; TBR-1; TES-56
基因别名: Tbr1
UniProt ID: (Mouse) Q64336
Entrez Gene ID: (Mouse) 21375
分子生物学功能: Rel homology transcription factor