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产品信息
MA5-31431
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL6251
抗原
Recombinant protein corresponding to Human TBX19
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2787067
产品详细信息
Immunogen sequence: EVHASTPGAF LLGNPAVTSP PSVLSTQAPT SAGVEVLGEP SLTSIAVSTW TAVASHPFAG WGGPGAGGHH SPSSLDG
靶标信息
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: T-box factor, pituitary; T-box protein 19; T-box transcription factor TBX19; TBS 19
基因别名: dJ747L4.1; TBS19; TBX19; TPIT
UniProt ID: (Human) O60806
Entrez Gene ID: (Human) 9095
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
anatomical structure morphogenesis
pituitary gland development
regulation of cell proliferation
cell fate commitment
regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
