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产品信息
PA5-143070
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-PFEPPTGKALSRKD.
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2933709
产品详细信息
Additional Information: This antibody is expected to recognize the reported isoform beta (NP_963998.2) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
靶标信息
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. This target is specific to isoform beta, endothelial receptor.
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生物信息学
蛋白别名: Prostanoid TP receptor; Thromboxane A2 receptor; TXA2-R
基因别名: BDPLT13; TBXA2R; TXA2-R
UniProt ID: (Human) P21731
Entrez Gene ID: (Human) 6915
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
response to nutrient
second-messenger-mediated signaling
response to lipopolysaccharide
thromboxane A2 signaling pathway
response to drug
positive regulation of GTPase activity
positive regulation of angiogenesis
positive regulation of blood pressure
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
